European Society of Toxicologic Pathology (ESTP)
    European Society of Toxicologic Pathology
ESTP/GTP meeting 2002: Case No 4
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Species: Cat
Strain/breeder: -
Sex: Spayed female
Age: 9 years
Study type: -
Treatment: Surgical removement
Animal status: Euthanized because of recurrency
Clinical findings:  
Organ(s): Subcutane mass at the shoulder
Macroscopic
finding(s):
Nodule of 7x5x6 cm in diamter, greyish-white surface; centraly cystic; no distinct border to surrounding tissue
Staining: H&E
Case 4, Fig. 1
Fig. 1 (87k)

Case 4, Fig. 2
Fig. 2 (88k)

Case 4, Fig. 3
Fig. 3 (60k)


Abstract

Feline vaccine-associated fibrosarcoma

T. BLEIER and M. REINACHER

Department of Veterinary Pathology, University of Giessen, Frankfurter Str. 96, 35392 Giessen, Germany

Key words: feline, fibrosarcoma, vaccination, giant cells

A spayed female European short hair cat (9 years) developed an expanding mass over a period of 6 month at the shoulder. The cat was vaccinated at this location one year before the tumour developed. Further data about previous vaccinations are unknown. The tumour was surgically removed.

Histologically a fibrosarcoma was diagnosed. The tumour consisted of pleomorphic cells, multinucleated giant cells, a large area of necrosis, and clusters of lymphocytes at the tumour periphery. Tumour cells exhibited a high mitotic rate of 4 per high power field.

Four weeks later the cat was euthanised because of tumour recurrency. Together with the vaccination history, the histologic findings lead to the diagnosis of a vaccine-associated feline fibrosarcoma (COUTO et al. (2002), Vet Pathol 39: 33-41).


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