 | |
| Digital slide: |
Case 1-1
Case 1-2 |
| Species: |
Rat |
| Strain/breeder: |
CRL:WI(GLX/BRL/HAN) IGS BR |
| Sex: |
Males |
| Age: |
1/1: 10 weeks, 1/2: 12 weeks |
| Study type: |
1/1: veterinary investigations, 1/2: carcinogenicity study |
| Treatment: |
None |
| Animal status: |
1/1: terminal sacrifice, 1/2: sacrificed moribund |
| Clinical findings: |
1/1: none, 1/2: bad general condition, weight loss, pale |
| Organ(s): |
Kidney |
Gross
finding(s): |
1/1: none, 1/2: kidneys: pale discoloration, enlarged, granulated surface; subcutaneous edema, edematous pancreas |
| Staining: |
H&E |
| Literature: |
| Palm M.: The incidence of chronic progressive nephrosis in young Sprague-Dawley rats from two different breeders. Laboratory Animals 1998, 32: 477-482 |
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