European Society of Toxicologic Pathology (ESTP)
    European Society of Toxicologic Pathology
ESTP Congress 2004: Case No 9b
case index | << previous case | next case >>
Digital slide:  
Species: Cynomolgus monkey
Strain/breeder: Mauritius
Sex: Male
Age: 4 years
Study type: 14 days treatment
Treatment: Cyclosporine (Neoral®) 150 mg/kg p.o. + steroids (Solu-medrol)
Animal status: 14 days post-transplantation (kidney allograft)
Clinical findings: Serum creatinine: 437 µmol/L; serum urea 40.3 mmol/L
Organ(s): Kidney allograft
Gross
finding(s):
Kidney enlarged; cut surface: pale
Staining: H&E
Literature:
Schuurman HJ, Menninger K, Audet M, Kunkler A, Maurer C, Vedrine C, Bernhard M, Gaschen L, Brinkmann V, Quesniaux V.: Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combinationwith cyclosporine or RAD. Transplantation. 2002, 74: 951-960

case index | << previous case | next case >>