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Digital slide: |
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Species: |
Cynomolgus monkey |
Strain/breeder: |
Mauritius |
Sex: |
Male |
Age: |
4 years |
Study type: |
14 days treatment |
Treatment: |
Cyclosporine (Neoral®) 150 mg/kg p.o. + steroids (Solu-medrol) |
Animal status: |
14 days post-transplantation (kidney allograft) |
Clinical findings: |
Serum creatinine: 437 µmol/L; serum urea 40.3 mmol/L |
Organ(s): |
Kidney allograft |
Gross finding(s): |
Kidney enlarged; cut surface: pale |
Staining: |
H&E |
Literature: |
Schuurman HJ, Menninger K, Audet M, Kunkler A, Maurer C, Vedrine C, Bernhard M, Gaschen L, Brinkmann V, Quesniaux V.: Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combinationwith cyclosporine or RAD. Transplantation. 2002, 74: 951-960 |
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